Friday, May 15, 2020
1:00 – 3:00pm
Location: Teleconferencing Platform
The CNS Board is delighted to announce our teleconference program for the annual Spring Conference. Our program this year features a local expert speaker, whose session will be both informative and thought-provoking. We intend on having a full day conference in the fall!
Featured Speaker Jim Grigsby – PhD, ABPP, Cancer Chemotherapy,
Cognition, and the Gut-Brain Axis
Cancer chemotherapy is associated with impaired cognition. This chemotherapy-related cognitive impairment (CRCI) affects a significant percentage of people undergoing cancer chemotherapy, and women with breast cancer comprise the best-studied population with the disorder. Prevalence estimates are crude, the features of chemotherapy-associated cognitive decline haven’t been definitively established, and the mechanism is unknown. Several etiologies have been hypothesized, but none has found significant support. Initially, several cognitive domains were implicated in CRCI, but better-designed studies with larger samples failed to replicate many of the early results, with the exception of a consistent finding of subjective complaints of cognitive decline in association with antineoplastic therapy. This frequently occurs in conjunction with fatigue, anxiety, depression, and depersonalization/derealization.
We are nearing completion of a preliminary study of the relationship between this syndrome and the microbial environment in the large intestine. The primary hypothesis is that many chemotherapeutic agents, in conjunction with other medications commonly prescribed to cancer patients—such as steroids and antibiotics—are associated with disruption of the gut microbiota, thereby affecting physical and psychological functioning.
This presentation provides an overview of CRCI, the relationship between the gut and the brain (known as the gut-brain axis), and a nearly-completed study of the hypothesis that CRCI may be a function of a central physiologic state that is altered in association with a disturbed microbial environment and dysregulated gut-brain axis.
Online Registration & Prices
Registration Deadline: May 8, 2020
Click the links below to pay via PayPal
CNS Member Student Free
(send email to info @ coloradoneuropsych.org to get your log-in credentials)
Non-CNS Member Student $15
(includes 2020 Membership fee)
Participants attending the conference will be able to:
- Identify the nature of the cognitive deficits associated with chemotherapy-related cognitive impairment (CRCI);
- Describe the incidence estimates for CRCI;
- Summarize chemotherapy-associated affective disorders independent of or comorbid with CRCI;
- Describe the gut microbiome, inflammation, and noncommunicable diseases;
- Summarize information presented the gut-brain axis and the vagus nerve;
This program includes 2.0 CE. The University of Denver, Graduate School of Professional Psychology (GSPP) is approved by the American Psychological Association to sponsor continuing education for psychologists. GSPP maintains responsibility for this program and its content.